People with the chronic skin condition psoriasis may be more likely to develop type 2 diabetes as well, according to an international study involving more than half a million people.
Researchers, whose results appeared in the Archives of Dermatology, found that this was especially true in those with severe psoriasis, who were 46 percent more likely to get a diabetes diagnosis than people without the condition, after weight and other health measures were taken into account.
Psoriasis is characterized by itchy, painful plaques on the skin. Previous studies have suggested the condition is tied to a higher chance of having heart disease, or suffering a heart attack or stroke, while other reports have hinted at a link between psoriasis and diabetes as well.
"We already knew that some of the risk factors for psoriasis and diabetes are similar, like weight," said Rahat Azfar, at the University of Pennsylvania in Philadelphia and lead author of the study.
"We do think that psoriasis itself makes people at higher risk."
For the study, Azfar and her colleagues consulted five years' worth of electronic medical records from about 108,000 adults in the UK with psoriasis, and about 400,000 without. None of them had diabetes at the outset.
They found that 3.7 percent of those with psoriasis were diagnosed with diabetes over the course of the study, compared with 3.4 percent of the comparison group.
When patients' age, weight and high blood pressure were accounted for, psoriasis was still tied to a higher chance of developing diabetes, especially among the 6,200 people with severe psoriasis. In that group, 6.3 percent were diagnosed with diabetes.
According to the study team, the body-wide inflammation that is seen both in people with psoriasis and type 2 diabetes may explain the link between the two conditions. Azfar said psoriasis may induce that chronic inflammation through changes in the bloodstream, thus upping the risk of diabetes.
It could also be that people with psoriasis are more depressed or exercise less, helping to explain the difference in diabetes rates, said Robert Kirsner, a dermatologist from the University of Miami Miller School of Medicine who has studied psoriasis but was not involved in the study.
So far, the data cannot prove that psoriasis directly causes diabetes. And there have not been any studies to show definitively whether the ointments, pills or injections used to treat psoriasis have any impact on a patient's chance of getting diabetes, Azfar added.
Kirsner said that patients with psoriasis should talk with their doctors about other ways to reduce their diabetes risks, such as by adopting a healthier lifestyle.
"(The study) suggests that patients with psoriasis perhaps should be followed more closely and may want to adhere to a better diet and all those things to prevent diabetes," he said.
Two of the researchers reported financial relationships with pharmaceutical companies, including those that make diabetes and psoriasis drugs. SOURCE: http://bit.ly/LBTfef
Guinea's President Alpha Conde announced new emergency measures in Ebola fight on Saturday
'Meetings happened. Action didn’t,' says Medecins Sans Frontieres report.
WHO said that on many levels, the world is better prepared now than ever before for aflu pandemic
Myanmar health officals say an outbreak of H5N1 bird flu in Mandalay
Tokyo Electric said it has been aware since last spring that radiation levels in water running in one of the plant gutters rise when it rains
Safe drinking water is available at about one-third of the level it was before the conflict erupted nearly five years ago, and supplies are cut-off to punish civilians at times
Elephants in Angola, which suffered decades of civil war, have been observed avoiding heavily-mined areas, suggesting their trunks were warning them to stay away.
Favipiravir halved death rate among some to 15 pct, but WHO says more research required on drug
The first medicine containing stem cells to treat a rare condition caused by burns to the eye has approved.
940 parasite samplescollected at 55 malaria treatment centres across Myanmar and its border regions. They found that almost 40 percent of the samples had mutations in their so-called kelch gene, K13 -- a known genetic signal of artemisinin drug resistance.
Yaws is known to be prevalent in 12 countries in areas where people have little access to healthcare, mainly in West and Central Africa, Asia and the Pacific Islands.
In the past few years, Nepal has seen the numbers of endangered species, such as the Royal Bengal tiger or the one-horned rhino, rise.
The investment would represent as little as 0.1 percent of current national health spending of the low and middle-income countries affected by NTD.
Nearly 1,000 abandoned California sea lions have washed ashore this year in what rehabilitation centers say is a growing crisis for the animals.
West Africa cases of Ebola show the first decrease in three weeks.
"Marijuana fools the brain's feeding system."scientist Tamas Horvath said.