If you have a relative who died of heart disease before age 60, your own risk of early heart trouble is higher as well, a study involving millions of people in Denmark over three decades has determined.
Family history of premature heart disease has long been considered a risk factor for heart problems in future generations, and the new study, which appeared in the Journal of the American College of Cardiology, strengthens this evidence.
Researchers found that people with a parent or sibling who died young of heart problems were roughly twice as likely as others to be diagnosed with coronary heart disease - where "plaques" build up in the heart arteries, raising the risk of heart attack before age 50.
They also had double the risk of suffering a ventricular arrhythmia, an often fatal rhythm disturbance in the heart's main pumping chamber.
"As with other chronic diseases, people should try to find out what they can about their family history," said Mattis Flyvholm Ranthe, the lead researcher on the study, in an email.
Researchers at the Statens Serum Institut in Copenhagen combed through public health data on almost four million Danish citizens born after 1949.
Between 1978 and 2008, almost 130,000 of them were diagnosed with some form of cardiovascular disease before age 50. Those odds were heightened when a first-degree relative had died of heart problems before hitting 60.
But those risks also were elevated when a second-degree relative, such as a grandparent or half-sibling, had died young. The risk of coronary disease, for example, was 43 percent higher in people with one second-degree relative who had died before age 60.
"This study tells us that a grandparent's history is meaningful too," said Amit Khera, who directs the preventative cardiology program at the University of Texas Southwestern Medical Center in Dallas.
The more relatives who died young, the greater the risk. When two or more first-degree relatives died of heart problems before age 60, a person's own risk of early heart disease rose five-fold.
It's not fully clear how much of a difference that lifestyle changes or medication for high blood pressure or cholesterol can make for people with heart disease in their family, but it's known that those steps help curb heart risk in general.
"There's no reason to suspect that preventive measures wouldn't apply to these folks as well," Khera said. SOURCE: bit.ly/PEP18s
The Ebola outbreak in West Africa has taken 1,552 lives out of 3,069 known cases in four countries and "continues to accelerate", WHO said
Presidential Press Secretary Jerolinmek Piah told AA the names would be announced later.
The WHO urged a range of "regulatory options", including prohibiting e-cigarette makers from making health claims
The doctor died after receiving the experimental drug ZMapp.
Japan has received inquiries from some countries on the influenza drug favipiravir, or T-705 as it is known in the developmental code.
Some 54 people have died in or near the capital Accra, and around 300 people are now being infected daily with the highly contagious disease, putting pressure on local health facilities, said Linda Van-Otoo, GHS director for Greater Accra.
A Philippine seaman is being monitored in Togo for signs of the disease but authorities say the country is still Ebola-free, despite dozens of workers returning from Liberia.
A 36-year-old man from Senegal is being tested in Barcelona.
MSF (Doctors Without Borders) has deployed 1,000 of its own staff in the stricken region, running centres that currently have 300 beds
On Wednesday, the residents of the two communities woke up just after the president ordered the quarantine only to find their community barricaded with soldiers and police officers preventing people from leaving or entering the two areas.
They were given ZMapp, a drug used on a handful of patients in the West African outbreak and produced by U.S.-based Mapp Biopharmaceutical.
A local priest who asked not to be named said that the illness had affected several villages and estimated that the death toll was over 100 people.
The calculation highlights the dilemma facing officials considering how to distribute the tiny quantities of unproven drugs that are likely to be available in the near term
"We are hopeful and grateful to God and to the medical team that they are showing signs of improvement," Liberia's Information Minister Lewis Brown told a press conference on Tuesday.
The decision came as the Ivorian national football team is due to face Sierra Leone, one of the countries that had been hard hit by the Ebola outbreak, next month in Abidjan as part of the Africa Cup of Nations 2015 qualifiers.
Infant products are particularly vulnerable to food safety scares in China after powdered milk tainted with the industrial chemical melamine led to the deaths of at least six infants in 2008