If you have a relative who died of heart disease before age 60, your own risk of early heart trouble is higher as well, a study involving millions of people in Denmark over three decades has determined.
Family history of premature heart disease has long been considered a risk factor for heart problems in future generations, and the new study, which appeared in the Journal of the American College of Cardiology, strengthens this evidence.
Researchers found that people with a parent or sibling who died young of heart problems were roughly twice as likely as others to be diagnosed with coronary heart disease - where "plaques" build up in the heart arteries, raising the risk of heart attack before age 50.
They also had double the risk of suffering a ventricular arrhythmia, an often fatal rhythm disturbance in the heart's main pumping chamber.
"As with other chronic diseases, people should try to find out what they can about their family history," said Mattis Flyvholm Ranthe, the lead researcher on the study, in an email.
Researchers at the Statens Serum Institut in Copenhagen combed through public health data on almost four million Danish citizens born after 1949.
Between 1978 and 2008, almost 130,000 of them were diagnosed with some form of cardiovascular disease before age 50. Those odds were heightened when a first-degree relative had died of heart problems before hitting 60.
But those risks also were elevated when a second-degree relative, such as a grandparent or half-sibling, had died young. The risk of coronary disease, for example, was 43 percent higher in people with one second-degree relative who had died before age 60.
"This study tells us that a grandparent's history is meaningful too," said Amit Khera, who directs the preventative cardiology program at the University of Texas Southwestern Medical Center in Dallas.
The more relatives who died young, the greater the risk. When two or more first-degree relatives died of heart problems before age 60, a person's own risk of early heart disease rose five-fold.
It's not fully clear how much of a difference that lifestyle changes or medication for high blood pressure or cholesterol can make for people with heart disease in their family, but it's known that those steps help curb heart risk in general.
"There's no reason to suspect that preventive measures wouldn't apply to these folks as well," Khera said. SOURCE: bit.ly/PEP18s
Travel across multiple time zones disrupts circadian rhythms resulting in jet lag
After five years the radiation levels in the Pacific Ocean are close to normal levels after a nuclear meltdown in the city
A trilateral pledge will see a jump from the current collective clean power levels of about 37% to 50% by 2025
Around 6.5 million deaths globally are attributed each year to poor air quality inside and outside, making it the world's fourth-largest threat to human health, behind high blood pressure, dietary risks and smoking
New World Drug Report research identifies heroin as deadliest drug
Zika has caused alarm throughout the Americas since cases of the birth defect microcephaly were reported in Brazil, the country hardest hit by the outbreak
Philadelphia has become the first big city in the US to place a tax on soda to tackle the obesity crisis
Average global temperatures startlingly higher than normal between March-May
Government study provides strongest evidence of cell phone health effects
The reason for the high-level threat in the area is the presence there of Aedes aegypti mosquitoes, which carry the Zika virus that health authorities say causes birth defects in newborns
Three-day African Utility Week conference begins in South African city of Cape Town
More than two thousand activists came together to close an opencast coal mine in Germany.
New federal rules unveiled on Thursday will tackle the release of the greenhouse gas methane from oil wells and equipment as part of an effort to fight climate change.
At least five reef islands in the remote Solomon Islands have been lost completely to sea level rise and coastal erosion
Heads of UN, Work Bank lay out vision to deal with climate change