"There is no justification for the closure of the Rafah crossing," Hamad al-Raqb, a spokesman for the protesters, said in a speech marking the beginning of a four-day sit-in.
"It is unbecoming of the historic relations between Egyptians and Palestinians," he insisted.
Leading Hamas figures and MPs attended the launch ceremony.
Egyptian authorities have tightened their control over the border with the Hamas-run Gaza Strip since last July's ouster of elected president Mohamed Morsi by the Egyptian army.
In recent weeks, Egypt has repeatedly closed the Rafah crossing, which – due to an ongoing, eight-year Israeli siege – represents Gaza's only window to the outside world.
The Egyptian army has also launched a campaign aimed at destroying the network of tunnels linking Gaza to Egypt's Sinai Peninsula, which in recent years had been used to bring vital commodities into the besieged coastal enclave, home to nearly 2 million Palestinians.
Hamas, an ideological offshoot of the Muslim Brotherhood, the group which propelled Morsi to power in the 2012 elections, has controlled the Gaza Strip, since 2007.
Muslim organizations in Europe have criticised a new law approved by the Austrian parliament, which aims to revise a historic law on the status of Muslims.
Egypt hopes the conference will bring in some $20 billion worth of investments.
Leading members of the Hamas, Fatah and Islamic Jihad movements led the protest, in which protesters waved Palestinian flags and shouted, "Down with Zionist terrorism"
"Some seem sensitive to this argument," Laurent Fabius and Philip Hammond wrote. "In reality, Bashar represents injustice, chaos and terror. We, France and Britain, say no to all three."
BMKG, Indonesia's meteorological agency, said the quake occurred in the middle of the ocean about 104 km northwest of East Flores.
Peshmerga forces prevent Arabs from returning to their homes in disputed territories claimed by Erbil and Baghdad, according to Human Rights Watch.
The capture of Tel Hamis was announced by the Kurdish YPG militia and confirmed by the Syrian Observatory for Human Rights, which monitors the country's civil war.
Unidentified militants bombed the home after accusing him of collaborating with the army.
The EU has already trained more than 4,000 Somali army soldiers since 2010 to fight insurgency in the region, EU Ambassador to Somalia Michele Cervone d'Urso said
Most of the capital's municipalities were told to be on high alert after floods killed 14 people in the city
The spokeswoman for prosecutors said there was currently no indication of involvement of a third party but the investigation was continuing.
Officials will hold more talks in Montreux, Switzerland
Italy's Chamber of Deputies voted by 300 to 45 to pass the motion presented by Prime Minister Matteo Renzi's Democratic Party
A police spokesman said federal police captured Gomez in Morelia, Michoacan's state capital, after months of intelligence work.
Syrian fighters trained in the program are expected to fight both Daesh and Assad regime.