"There is no justification for the closure of the Rafah crossing," Hamad al-Raqb, a spokesman for the protesters, said in a speech marking the beginning of a four-day sit-in.
"It is unbecoming of the historic relations between Egyptians and Palestinians," he insisted.
Leading Hamas figures and MPs attended the launch ceremony.
Egyptian authorities have tightened their control over the border with the Hamas-run Gaza Strip since last July's ouster of elected president Mohamed Morsi by the Egyptian army.
In recent weeks, Egypt has repeatedly closed the Rafah crossing, which – due to an ongoing, eight-year Israeli siege – represents Gaza's only window to the outside world.
The Egyptian army has also launched a campaign aimed at destroying the network of tunnels linking Gaza to Egypt's Sinai Peninsula, which in recent years had been used to bring vital commodities into the besieged coastal enclave, home to nearly 2 million Palestinians.
Hamas, an ideological offshoot of the Muslim Brotherhood, the group which propelled Morsi to power in the 2012 elections, has controlled the Gaza Strip, since 2007.
Iraq suffers from acute financial crisis due to dropped oil prices and anti-terrorism expenses
Thousands of supporters poured into the streets of the capital island Male on Friday night and continued their protest rally till early Saturday, the joint opposition said in a statement issued in Colombo.
Also suspended were the accounts of its parent organization, Strategic Communication Laboratories, as well as those of University of Cambridge psychologist Aleksandr Kogan and Christopher Wylie, who runs Eunoia Technologies.
Andrew McCabe was accused of misleading investigators on Clinton Foundation corruption case
Assistant Secretary of State Wess Mitchell told reporters after talks with Cypriot President Nicos Anastasiades on Friday that the U.S. also wants to see a resumption of talks to reunify the ethnically divided island nation.
"There were seven people aboard, they are all believed to be dead," the official said, adding they were US service members.
A doctor at the private Goyal Hospital told AFP Friday that Clinton had undergone screening after suffering pain in her right hand following a fall.
The alliance is "dealing with the issue around this and in cyber and working to define an understanding of what would be a trigger for Article 5," General Curtis Scaparrotti, the commander of NATO forces in Europe, told a US Senate committee.
Speaking to reporters as he returned from a trip to Oman, Afghanistan and Bahrain, Mattis said officials he met with had expressed frequent concerns about Iranian behavior.
The newspaper said that Trump is discussing potential replacements for McMaster, but is willing to take his time because he wants to avoid humiliating him as well as to have a successor ready.
19 individuals, 5 entities blacklisted by Washington
Saeb Erekat slams recent White House meeting on Gaza's deteriorating humanitarian situation
Salim al-Jabouri says Turkey and Iraq will defeat terrorism together through 'full cooperation'
Oil is the lifeblood of OPEC member Venezuela's economy, but a major wave of political unrest that shows no sign of abating has slashed output.