He said that "something dramatic" must come out of George Bush's meeting with Nuri al-Maliki, the Iraqi prime minister, to stop the violence.
TheUnited States must look at the "big picture" and seek Middle Eastern solutions involving all the regional players, he told ABC's This Week programme.
He said there would be another decade or two of violence if a regional peace process was not developed soon.
Abdullah hoped al-Maliki would have ideas for Bush on how to be "inclusive" in bringing together different groups in Iraq.
"And they need to do it now, because, obviously, as we're seeing, things are beginning to spiral out of control ... there needs to be some very strong action taken on the ground there today," he said.
In a separate interview, Iraq's security adviser said that Iraq was already a regional battleground, with Islamic movements from several Arab countries funding the groups fighting the Iraqi government and the US army.
"It's not one country. It's not two countries. It is more than that," Mowaffak al-Rubaie told CNN's Late Edition.
"This is a fight, or this is a war between the extremists and the moderates in the whole region."
He added that Iran was "helping some of the extremist Shia groups in Iraq," but said there was no evidence Iran was helping al-Qaeda or anti-government fighters in Iraq.
Jordan's King Abdullah said the Israeli-Palestinian conflict remained the "emotional core issue" of the Middle East.
Jordan is home to the largest number of Palestinians outside the West Bank and Gaza Strip.
Asked if Syria and Iran should be included in an international conference on the Middle East, he said: "the problem is, that America needs to look at it in the total picture. It's not just one issue by itself."
"Palestine is the core. It is linked to the extent of what's going on in Iraq. It is linked to what's going on in Lebanon. It is linked to the issues that we find ourselves with the Syrians. So, if you want to do comprehensive - comprehensive means bringing all the parties of the region together."