Obese kids have more asthma flare-ups

Both asthma and obesity rates have soared among kids in recent decades, reaching nearly 10 percent and 17 percent today, respectively.

Obese kids have more asthma flare-ups

Shaving off extra pounds might help asthmatic kids prevent flare-ups of the disease, according to a study that found obese children have a harder time controlling their symptoms.

The work is the first to show that even after taking race and social factors into account, heavier kids use more drugs to control their asthma and curb flare-ups than their slimmer peers.

"Improving nutritional status, preventing obesity, and stressing the importance of weight loss might improve asthma control and exacerbation risk in children and decrease the incidence of asthma in adults," researchers write in the Journal of Allergy and Clinical Immunology.

Both asthma and obesity rates have soared among kids in recent decades, reaching nearly 10 percent and 17 percent today, respectively.

While some studies have hinted at a link between the two conditions, conclusions on whether heavier kids also have more severe asthma than others have been mixed.

Dr. Kenneth B. Quinto from the University of California, San Diego, and colleagues looked back at more than 32,000 kids who'd been diagnosed with asthma and were enrolled in a Kaiser Permanente health plan. Nearly half of the children were overweight or obese.

The researchers found that the heavier kids were more likely to have more than a handful of yearly prescriptions for rescue inhalers, which contain short-acting drugs such as albuterol that open up the airways when an asthma attack is coming on.

On average, normal-weight children used 2.8 rescue inhalers a year, whereas obese kids used 3.1.

The heavy youngsters also used more inhaled steroids, such as Pulmicort or Flovent, which are a mainstay treatment to keep airway inflammation under control on a daily basis in asthmatics.

And the results held up after Quinto and his colleagues accounted for alternative explanations of the differences, such as sex, race, diabetes and parents' education levels.

The team speculates that the extra pounds might be weighing on the lungs, making obese kids feel like they need more medication. Scientists have also found that overweight people don't respond as well as others to steroids, which might help explain the new findings.

Still, in an observational study like theirs, the researchers warn it's never possible to be certain what causes what. So whether bigger waistlines should be blamed for the extra flare-ups remains an open question.

Meanwhile, the team writes, "The best time for prevention of obesity and nonsurgical weight reduction likely occurs in childhood."


Last Mod: 03 Eylül 2011, 10:11
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