Israeli authorities will close the Ibrahimi Mosque in the West Bank city of Hebron to Muslim worshippers on Sunday and Monday within the context of religious celebrations of Jewish citizens.
Tayseer Abu Sneina, director of Islamic endowments authority in the city, has been notified of the Israeli decision of closing the mosque for Muslims.
"This is an act of aggression against a place of worship and an affront to Muslims," the authority said.
The Ibrahimi Mosque, holy to both Muslim and Jewish religions is widely believed to mark the burial sites of prophets Abraham, Isaac, Jacob and their wives.
Following the 1994 massacre of 29 Palestinian worshippers inside the mosque by Jewish extremist settler Baruch Goldstein, Israel decided to keep Muslim and Jewish worshippers separated.
The city of Hebron (Al-Khalil) is home to about 160,000 Palestinian Muslims and roughly 500 Jewish settlers.
The latter live in several Jewish-only enclaves that are heavily guarded by Israeli troops.