Numan Kurtulmus told a routine Syrian Coordination Committee meeting in Ankara on Wednesday: "This (conflict) is a shame on humanity that transcends the borders of Syria.
"Unfortunately, world powers do not have an ounce of perspective on how to stop this state terror."
"Those who seek to harness regional or global power over the Syrian crisis ... history will rank them among the culprits of this tragedy," he declared.
The four-year-old crisis had led to the deaths of more than 190,000 people, according to U.N. estimates in August last year.
Violence has torn families apart, destroyed entire cities and displaced nearly half of the 23-million population.
Turkey has been among the countries worst-hit by the refugee crisis, hosting close to two million shelter-seekers, a mission that has cost the government an estimated $5 billion.
During Wednesday’s meeting, Kurtulmus also announced the launch of the Islahiyah refugee camp in southern Turkey - the 23rd government-run camp on the border with capacity for 35,000 people.
The total number of Syrian and Iraqi refugees living in the camps has reached 235,000, the deputy prime minister said.
Kurtulmus also revealed the government would provide Iraqi refugees - who used to only benefit from emergency care - with full-fledged healthcare services.
Iraq has been in turmoil since early last year when the extremist group ISIL captured the city of Fallujah in central Iraq.
ISIL then seized Iraq's second city, Mosul, in June, catching Tehran and world powers off guard with an all-out military campaign that tore through the Middle Eastern country.