The ten defendants are being tried on charges of ordering the killing of demonstrators upon the January 25 revolution, which brought Mubarak's three-decades of rule to an end in 2011.
Former military police commander Hamdi Badeen, who is now Egypt's military attaché in China, is expected to testify during the session, which is held at the Police Academy on the eastern outskirts of Cairo where the trial of ousted president Mohamed Morsi on charges of inciting the killing of demonstrators, is also held.
The Executive President of the Egyptian National Telecommunications Regulatory Authority Amr Badawi is also expected to testify during the session.
The backers of Mubarak, who now receives treatment at a southern Cairo military hospital, converged on the vicinity of the court.
The judge presiding over the trial has banned the live broadcast of trial sessions until he hears the accounts of the witnesses.
The former president, his two sons, and a business tycoon are also accused of financial corruption.